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Estimating the Financial Impact of Gene Therapy in the U.S. -- by Chi Heem Wong, Dexin Li, Nina Wang, Jonathan Gruber, Rena M. Conti, Andrew W. Lo
We empirically assess the potential financial impact of future gene therapies on the US economy. After identifying 109 late-stage gene therapy clinical trials currently underway, we estimate the number of new and existing patients with corresponding diseases to be treated by these gene therapies, developing and applying novel mathematical models to estimate the increase in […]
The Production and Consumption of Social Media -- by Apostolos Filippas, John J. Horton
We model social media as collections of users producing and consuming content. Users value consuming content, but doing so uses up their scarce attention, and hence they prefer content produced by more able users. Users also value receiving attention, creating the incentive to attract an audience by producing valuable content, but also through attention bartering—users […]
Technology and the Task Content of Jobs across the Development Spectrum -- by Julieta Caunedo, Elisa Keller, Yongseok Shin
Technology is the driver of labor allocation across sectors and occupations. Is the impact of technological change on developing countries similar to its impact on developed countries? Will developing countries follow the same development path that developed economies have taken? Our approach focuses on how technology shifts and reshapes the tasks workers perform on the […]
How Do Business Owners Respond to a Tax Cut? Examining the 199A Deduction for Pass-through Firms -- by Lucas Goodman, Katherine Lim, Bruce Sacerdote, Andrew Whitten
We consider the short-run responses of businesses and their owners to the introduction of Section 199A, a deduction implemented in 2018 that reduced the effective tax rate on pass-through business income. We study the deduction using several datasets derived from de-identified tax records of individuals and businesses. Overall, we do not find an increase in […]
Venture Capital’s “Me Too” Moment -- by Sophie Calder-Wang, Paul Gompers, Patrick Sweeney
In this paper, we document the historically low rate of hiring of women in the venture capital sector. We find that the high-profile Ellen Pao v. Kleiner Perkins gender discrimination trial had dramatic treatment effects. In difference-in-differences regressions, we find that the rate of hiring of female venture capitalists increased substantially after the trial and […]
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